Delius Lab – Publications: Dynamic Systems

64: The Dynamic Chemistry of Orthoesters and Trialkoxysilanes: Making Supramolecular Hosts Adaptive, Fluxional and Degradable

S. Hollstein, M. von Delius
Acc. Chem. Res. 2024, 57, 602–612

graphical abstract showing a general structure and aggregation properties of acylphosphates

63: Acylphosphates as versatile transient species in reaction networks and optical catalyst screenings

A. Englert, F. Majer, J. L. Schiessl, A. J. C. Kuehne, M. von Delius
Chem, 2024, 10, 910–923

Also available as preprint on ChemRXiv.

58: Supramolecular Polymerization of all-cis Fluorinated Cyclohexanes: Influence of Side Chains

S. V. Haridas, O. Shyshov, M. von Delius
Org. Mater. 2023, 5, 166‒174

graphical abstract showing trialkoxysilane exchange and a trialkoxysilane cryptate

57: Trialkoxysilane Exchange: Scope, Mechanism, Cryptates and pH-Response

S. Hollstein, P. Erdmann, A. Ulmer, H. Löw, L. Greb, M. von Delius
Angew. Chem. Int. Ed. 2023, 62, e202304083

Selected as “Hot Paper”.

56: Steric Control over the Threading of Pyrophosphonates with One or Two Cyanostar Macrocycles during Pseudorotaxane Formation

J. Vogel, Y. Chen, R. E. Fadler, A. H. Flood, M. von Delius
Chem. Eur. J. 2023, 29, e202300899

55: Into the Dynamics of Rotaxanes at Atomistic Resolution

L. Leanza, C. Perego, L. Pesce, M. Salvalaglio, M. von Delius, G. M. Pavan
Chem. Sci. 2023, 14, 6716‒6729

Also available as preprint on ChemRXiv.

52: A triazolium-anchored self-immolative linker enables self-assembly-driven siRNA binding and esterase-induced release

S. Hollstein, L. M. A. Ali, M. Coste, J. Vogel, N. Bettache, S. Ulrich, M. von Delius
Chem. Eur. J. 2023, 29, e202203311

51: A Ribonucleotide ↔ Phosphoramidate Reaction Network Optimized by Computer-Aided Design

A. Englert, J. F. Vogel, T. Bergner, J. Loske, M. von Delius
J. Am. Chem. Soc. 2022, 144, 15266–15274

50: Anion-assisted amidinium exchange and metathesis

O. Borodin, Y. Shchukin, J. Schmid, M. von Delius
Chem. Commun. 2022, 58, 10178‒10181

49: Dynamic Covalent Self-Assembly of Chloride- and Ion-Pair-Templated Cryptates

S. Hollstein, O. Shyshov, M. Hanževački, J. Zhao, T. Rudolf, C. M. Jäger, M. von Delius
Angew. Chem. Int. Ed. 2022, 134, e202201831

Highlighted in ERC “Research results of the week”. Also published in German, translated by Selina Hollstein. Highlighted on the journal inside cover

47: Carbodiimide-driven dimerization and self-assembly of artificial, ribose-based amphiphiles

J. Sun, J. Vogel, L. Chen, A. L. Schleper, T. Bergner, A. J. C. Kuehne, M. von Delius
Chem. Eur. J. 2022, 28, e202104116

Highlight in Mandarin: 碳二亚胺驱动的核糖核苷酸类两亲化合物的二聚化及自组装; Part of Special Collection in memory of Klaus Hafner.

43: Self-assembly of stimuli-responsive [2]rotaxanes by amidinium exchange

O. Borodin, Y. Shchukin, C. C. Robertson, S. Richter, M. von Delius
J. Am. Chem. Soc. 2021, 143, 16448‒16457

42: Living Supramolecular Polymerization of Fluorinated Cyclohexanes

O. Shyshov, S. V. Haridas, L. Pesce, H. Qi, A. Gardin, D. Bochicchio, U. Kaiser, G. M. Pavan, M. von Delius
Nat. Commun. 2021, 12, 3134

Selected as Editor’s Highlight.

animation showing a 3d structure of supramolecular three-shell complex based on cubic organometallic cage, fullerene, and [10]CPP

41: A three-shell supramolecular complex enables the symmetry-mismatched chemo- and regioselective bis-functionalization of C60

E. Ubasart, O. Borodin, C. Fuertes-Espinosa, Y. Xu, C. García-Simón, J. Juanhuix, F. Gándara, I. Imaz, D. Maspoch, M. von Delius, X. Ribas
Nat. Chem. 2021, 13, 420‒427

Press release in English and German; Highlighted on the journal front cover and in C&EN, Chemistry Views, Nanowerk, ChemEurope, Laborpraxis, ChemistryCommunity; Animated Gif by Agustí Lledó.

38: Dynamic covalent formation of concave disulfide macrocycles mechanically interlocked with single-walled carbon nanotubes

B. Balakrishna, A. Menon, K. Cao, S. Gsänger, S. B. Beil, J. Villalva, O. Shyshov, O. Martin, A. Hirsch, B. Meyer, U. Kaiser, D. M. Guldi, M. von Delius
Angew. Chem. Int. Ed. 2020, 59, 18774‒18785

Selected as VIP Paper. Highlighted in ChemistryViews. Graphical Abstract gif created by VH Shyamkumar.

graphical abstract showing interconversion of orthoester cryptands

36: Self-Assembly, Adaptive Response and in,out-Stereoisomerism of Large Orthoformate Cryptands

H. Löw, E. Mena-Osteritz, K. M. Mullen, C. M. Jäger, M. von Delius
ChemPlusChem 2020, 85, 108–112

Invited Contribution to the Special Collection “Supramolecular Chemistry: Young Talents and their Mentors”. Highlighted in ChemistryViews.

graphical abstract showing reaction schemes of trithioorthoester exchange and metathesis

33: Trithioorthoester Exchange and Metathesis: New Tools for Dynamic Covalent Chemistry

M. Bothe, G. Orrillo, R. Furlan, M. von Delius
Synlett 2019, 30, 1988–1994

Invited contribution to the Special Issue “Metathesis beyond Olefins“ edited by Bill Morandi.

graphical abstract showing formation of a cryptand and a cryptate via orthoester exchange

32: Self-templated synthesis of an orthoformate in,in-cryptand and its bridgehead inversion by dynamic covalent exchange

H. Löw, E. Mena-Osteritz, M. von Delius
Chem. Commun. 2019, 55, 11434-11437

graphical abstract showing structural changes in orthoester cryptands

31: Ammonium Complexes of Orthoester Cryptands are Inherently Dynamic and Adaptive

X. Wang, O. Shyshov, M. Hanževački, C. Jäger, M. von Delius
J. Am. Chem. Soc. 2019, 141, 8868−8876

graphical abstract showing orthoesters with their precursors and a food chain

30: Über den Trend vom Molekül zum System

M. von Delius, S. Hollstein
Nachrichten aus der Chemie 2019, 67, 62–65

graphical abstract showing reaction scheme of orthoester polymerization

29: Long-Chain Polyorthoesters as Degradable Polyethylene Mimics

T. Haider, O. Shyshov, O. Suraeva, I. Lieberwirth, M. von Delius, F. R. Wurm
Macromolecules 2019, 52, 2411−2420

graphical abstract showing x-ray structures of orthoester cryptates and their transformations

26: Self-Assembled Orthoester Cryptands: Orthoester Scope, Post-Functionalization, Kinetic Locking and Tunable Degradation Kinetics

H. Löw, E. Mena-Osteritz, M. von Delius
Chem. Sci. 2018, 9, 4785–4793

graphical abstract showing solid-state structure of complex between chloride and hexafluorocyclohexane

25: Evidence for anion-binding of all-cis hexafluorocyclohexane in solution and solid state

O. Shyshov, K. A. Siewerth, M. von Delius
Chem. Commun. 2018, 54, 4353–4355

24: Disulfide-centered poly(methyl acrylates): four different stimuli to cleave a polymer

U. F. Fritze, S. L. Craig, M. von Delius
J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 1404‒1411

21: Adaptive Behaviour of Dynamic Orthoester Cryptands

O. Shyshov, R. Brachvogel, T. Bachmann, R. Srikantharajah, D. Segets, F. Hampel, R. Puchta, M. von Delius
Angew. Chem. Int. Ed. 2017, 56, 776‒781